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BMCBI
2010
108views more  BMCBI 2010»
15 years 4 months ago
Prediction of RNA secondary structure by maximizing pseudo-expected accuracy
Background: Recent studies have revealed the importance of considering the entire distribution of possible secondary structures in RNA secondary structure predictions; therefore, ...
Michiaki Hamada, Kengo Sato, Kiyoshi Asai
BMCBI
2011
15 years 2 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
BMCBI
2011
15 years 2 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
MICCAI
2009
Springer
16 years 1 months ago
Optical Biopsy Mapping for Minimally Invasive Cancer Screening.
The quest for providing tissue characterization and functional mapping during minimally invasive surgery (MIS) has motivated the development of new surgical tools that extend the...
Peter Mountney, Stamatia Giannarou, Daniel Elson...
BMCBI
2011
14 years 10 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...