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ALMOB
2006
109views more  ALMOB 2006»
15 years 6 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
190
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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 6 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
149views more  BMCBI 2006»
15 years 6 months ago
Identification of biomarkers from mass spectrometry data using a "common" peak approach
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
Tadayoshi Fushiki, Hironori Fujisawa, Shinto Eguch...
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...
CORR
2006
Springer
119views Education» more  CORR 2006»
15 years 6 months ago
Clustering and Sharing Incentives in BitTorrent Systems
Peer-to-peer protocols play an increasingly instrumental role in Internet content distribution. It is therefore important to gain a complete understanding of how these protocols b...
Arnaud Legout, Nikitas Liogkas, Eddie Kohler, Lixi...