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BMCBI
2006
81views more  BMCBI 2006»
15 years 6 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
BMCBI
2006
175views more  BMCBI 2006»
15 years 6 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
BMCBI
2006
165views more  BMCBI 2006»
15 years 6 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2006
129views more  BMCBI 2006»
15 years 6 months ago
Independent Component Analysis-motivated Approach to Classificatory Decomposition of Cortical Evoked Potentials
Background: Independent Component Analysis (ICA) proves to be useful in the analysis of neural activity, as it allows for identification of distinct sources of activity. Applied t...
Tomasz G. Smolinski, Roger Buchanan, Grzegorz M. B...
BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
A methodology for global validation of microarray experiments
Background: DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray st...
Mathieu Miron, Owen Z. Woody, Alexandre Marcil, Ca...