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BMCBI
2008
86views more  BMCBI 2008»
15 years 6 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
BMCBI
2006
88views more  BMCBI 2006»
15 years 6 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
BMCBI
2006
112views more  BMCBI 2006»
15 years 6 months ago
Phylophenetic properties of metabolic pathway topologies as revealed by global analysis
Background: As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components. In the post-genomic e...
Yong Zhang, Shaojuan Li, Geir Skogerbø, Zhi...
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
PLDI
2011
ACM
14 years 9 months ago
Systematic editing: generating program transformations from an example
Software modifications are often systematic—they consist of similar, but not identical, program changes to multiple contexts. Existing tools for systematic program transformati...
Na Meng, Miryung Kim, Kathryn S. McKinley