Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Background: As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components. In the post-genomic e...
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
Software modifications are often systematic—they consist of similar, but not identical, program changes to multiple contexts. Existing tools for systematic program transformati...