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BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi
BMCBI
2006
154views more  BMCBI 2006»
15 years 6 months ago
Analysis with respect to instrumental variables for the exploration of microarray data structures
Background: Evaluating the importance of the different sources of variations is essential in microarray data experiments. Complex experimental designs generally include various fa...
Florent Baty, Michaël Facompré, Jan Wi...
BMCBI
2006
146views more  BMCBI 2006»
15 years 6 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2006
121views more  BMCBI 2006»
15 years 6 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...