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BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
Detecting internally symmetric protein structures
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Changhoon Kim, Jodi Basner, Byungkook Lee
BMCBI
2010
108views more  BMCBI 2010»
15 years 6 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2010
82views more  BMCBI 2010»
15 years 6 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...
BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
Comparative optimism in models involving both classical clinical and gene expression information
Background: In cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: r...
Caroline Truntzer, Delphine Maucort-Boulch, Pascal...
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Simple and flexible classification of gene expression microarrays via Swirls and Ripples
Background: A simple classification rule with few genes and parameters is desirable when applying a classification rule to new data. One popular simple classification rule, diagon...
Stuart G. Baker