Sciweavers

21324 search results - page 540 / 4265
» Making the case for computing
Sort
View
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
15 years 6 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
BIBM
2010
IEEE
222views Bioinformatics» more  BIBM 2010»
15 years 5 months ago
CEO a cloud epistasis computing model in GWAS
The 1000 Genome project has made available a large number of single nucleotide polymorphisms (SNPs) for genome-wide association studies (GWAS). However, the large number of SNPs ha...
Zhengkui Wang, Yue Wang, Kian-Lee Tan, Limsoon Won...
CAD
2011
Springer
15 years 2 months ago
Computing the minimum enclosing sphere of free-form hypersurfaces in arbitrary dimensions
The problem of computing the minimum enclosing sphere (MES) of a point set is a classical problem in Computational Geometry. As an LP-type problem, its expected running time on th...
Ramanathan Muthuganapathy, Gershon Elber, Gill Bar...
DAC
2006
ACM
16 years 8 months ago
Criticality computation in parameterized statistical timing
Chips manufactured in 90 nm technology have shown large parametric variations, and a worsening trend is predicted. These parametric variations make circuit optimization difficult ...
Jinjun Xiong, Vladimir Zolotov, Natesan Venkateswa...
CHI
2001
ACM
16 years 7 months ago
Beyond command knowledge: identifying and teaching strategic knowledge for using complex computer applications
Despite experience, many users do not make efficient use of complex computer applications. We argue that this is caused by a lack of strategic knowledge that is difficult to acqui...
Suresh K. Bhavnani, Frederick Reif, Bonnie E. John