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BMCBI
2010
163views more  BMCBI 2010»
15 years 6 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
CORR
2010
Springer
122views Education» more  CORR 2010»
15 years 6 months ago
Harvesting Collective Intelligence: Temporal Behavior in Yahoo Answers
When harvesting collective intelligence, a user wishes to maximize the accuracy and value of the acquired information without spending too much time collecting it. We empirically ...
Christina Aperjis, Bernardo A. Huberman, Fang Wu
BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2007
164views more  BMCBI 2007»
15 years 6 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...