26071 search results - page 4891 / 5215 » Making |
145
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BMCBI
2006
15 years 6 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
177
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BMCBI
2006
15 years 6 months ago
2006
Background: Bacterial typing schemes based on the sequences of genes encoding surface antigens require databases that provide a uniform, curated, and widely accepted nomenclature ...
221
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BMCBI
2006
15 years 6 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
168
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BMCBI
2006
15 years 6 months ago
2006
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
204
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BMCBI
2006
15 years 6 months ago
2006
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...