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BMCBI
2006
133views more  BMCBI 2006»
15 years 6 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
186
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BMCBI
2006
119views more  BMCBI 2006»
15 years 6 months ago
Hidden Markov Model Variants and their Application
Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way...
Stephen Winters-Hilt
BMCBI
2006
155views more  BMCBI 2006»
15 years 6 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
BMCBI
2006
95views more  BMCBI 2006»
15 years 6 months ago
Discrete profile comparison using information bottleneck
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
BMCBI
2006
150views more  BMCBI 2006»
15 years 6 months ago
TreeDyn: towards dynamic graphics and annotations for analyses of trees
Background: Analyses of biomolecules for biodiversity, phylogeny or structure/function studies often use graphical tree representations. Many powerful tree editors are now availab...
François Chevenet, Christine Brun, Anne-Lau...
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