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BMCBI
2005
122views more  BMCBI 2005»
15 years 6 months ago
A neural strategy for the inference of SH3 domain-peptide interaction specificity
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...
Enrico Ferraro, Allegra Via, Gabriele Ausiello, Ma...
BMCBI
2004
185views more  BMCBI 2004»
15 years 6 months ago
Linear fuzzy gene network models obtained from microarray data by exhaustive search
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
Bahrad A. Sokhansanj, J. Patrick Fitch, Judy N. Qu...
PR
2007
100views more  PR 2007»
15 years 6 months ago
Linear manifold clustering in high dimensional spaces by stochastic search
Classical clustering algorithms are based on the concept that a cluster center is a single point. Clusters which are not compact around a single point are not candidates for class...
Robert M. Haralick, Rave Harpaz
ISDA
2010
IEEE
15 years 4 months ago
Avoiding simplification strategies by introducing multi-objectiveness in real world problems
Abstract--In business analysis, models are sometimes oversimplified. We pragmatically approach many problems with a single financial objective and include monetary values for non-m...
Charlotte J. C. Rietveld, Gijs P. Hendrix, Frank T...
BMCBI
2010
182views more  BMCBI 2010»
15 years 6 months ago
L2-norm multiple kernel learning and its application to biomedical data fusion
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
Shi Yu, Tillmann Falck, Anneleen Daemen, Lé...