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BMCBI
2010
111views more  BMCBI 2010»
15 years 6 months ago
Functional Analysis: Evaluation of Response Intensities - Tailoring ANOVA for Lists of Expression Subsets
Background: Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions....
Fabrice Berger, Bertrand De Meulder, Anthoula Gaig...
BMCBI
2008
160views more  BMCBI 2008»
15 years 6 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
BMCBI
2008
169views more  BMCBI 2008»
15 years 6 months ago
A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2007
114views more  BMCBI 2007»
15 years 6 months ago
False occurrences of functional motifs in protein sequences highlight evolutionary constraints
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
Allegra Via, Pier Federico Gherardini, Enrico Ferr...