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BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
ProbABEL package for genome-wide association analysis of imputed data
Background: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, impute...
Yurii S. Aulchenko, Maksim V. Struchalin, Cornelia...
BMCBI
2004
135views more  BMCBI 2004»
15 years 6 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
SOICT
2010
15 years 1 months ago
Constraint-based local search for solving non-simple paths problems on graphs: application to the routing for network covering p
Routing problems have been considered as central problems in the fields of transportation, distribution and logistics. LS(Graph) is a generic framework allowing to model and solve...
Pham Quang Dung, Phan-Thuan Do, Yves Deville, Tuon...
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BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2005
137views more  BMCBI 2005»
15 years 6 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...