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BMCBI
2010
96views more  BMCBI 2010»
15 years 6 months ago
sdef: an R package to synthesize lists of significant features in related experiments
Background: In microarray studies researchers are often interested in the comparison of relevant quantities between two or more similar experiments, involving different treatments...
Marta Blangiardo, Alberto Cassese, Sylvia Richards...
BMCBI
2010
100views more  BMCBI 2010»
15 years 6 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2008
87views more  BMCBI 2008»
15 years 6 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2008
114views more  BMCBI 2008»
15 years 6 months ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...
BMCBI
2010
155views more  BMCBI 2010»
15 years 6 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe