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BMCBI
2007
194views more  BMCBI 2007»
15 years 6 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
BMCBI
2010
145views more  BMCBI 2010»
15 years 6 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
CORR
2010
Springer
259views Education» more  CORR 2010»
15 years 6 months ago
Community Detection in Networks: The Leader-Follower Algorithm
Natural networks such as those between humans observed through their interactions or biological networks predicted based on various experimental measurements contain a wealth of i...
Devavrat Shah, Tauhid Zaman
BMCBI
2006
152views more  BMCBI 2006»
15 years 6 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
ML
2008
ACM
101views Machine Learning» more  ML 2008»
15 years 6 months ago
On reoptimizing multi-class classifiers
Significant changes in the instance distribution or associated cost function of a learning problem require one to reoptimize a previously-learned classifier to work under new cond...
Chris Bourke, Kun Deng, Stephen D. Scott, Robert E...