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BMCBI
2011
15 years 1 months ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
KDD
2006
ACM
240views Data Mining» more  KDD 2006»
16 years 7 months ago
Adaptive event detection with time-varying poisson processes
Time-series of count data are generated in many different contexts, such as web access logging, freeway traffic monitoring, and security logs associated with buildings. Since this...
Alexander T. Ihler, Jon Hutchins, Padhraic Smyth
BMCBI
2010
145views more  BMCBI 2010»
15 years 7 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
BMCBI
2008
143views more  BMCBI 2008»
15 years 7 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
SIGMOD
2011
ACM
242views Database» more  SIGMOD 2011»
14 years 9 months ago
The SystemT IDE: an integrated development environment for information extraction rules
Information Extraction (IE) — the problem of extracting structured information from unstructured text — has become the key enabler for many enterprise applications such as sem...
Laura Chiticariu, Vivian Chu, Sajib Dasgupta, Thil...