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BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Correction of scaling mismatches in oligonucleotide microarray data
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
BMCBI
2006
81views more  BMCBI 2006»
15 years 6 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
BMCBI
2006
118views more  BMCBI 2006»
15 years 6 months ago
Identification of gene expression patterns using planned linear contrasts
Background: In gene networks, the timing of significant changes in the expression level of each gene may be the most critical information in time course expression profiles. With ...
Hao Li, Constance L. Wood, Yushu Liu, Thomas V. Ge...
BMCBI
2006
163views more  BMCBI 2006»
15 years 6 months ago
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological featur
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
J. R. Semeiks, A. Rizki, Mina J. Bissell, I. Saira...
BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
Cornelis A. Albers, Martijn A. R. Leisink, Hilbert...
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