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169
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BMCBI
2007
15 years 6 months ago
2007
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
153
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BMCBI
2007
15 years 6 months ago
2007
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
184
Voted
BMCBI
2007
15 years 6 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
204
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BMCBI
2008
15 years 6 months ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
190
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EC
2010
15 years 6 months ago
2010
Memetic algorithms with continuous local search methods have arisen as effective tools to address the difficulty of obtaining reliable solutions of high precision for complex cont...