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BMCBI
2010
159views more  BMCBI 2010»
15 years 7 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2008
134views more  BMCBI 2008»
15 years 7 months ago
Stability analysis of mixtures of mutagenetic trees
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
Jasmina Bogojeska, Thomas Lengauer, Jörg Rahn...
BMCBI
2007
126views more  BMCBI 2007»
15 years 7 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2008
179views more  BMCBI 2008»
15 years 7 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2008
112views more  BMCBI 2008»
15 years 7 months ago
A simplified approach to disulfide connectivity prediction from protein sequences
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...