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BIOCOMP
2006
15 years 7 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
ICMLA
2008
15 years 7 months ago
Microarray Classification from Several Two-Gene Expression Comparisons
We describe our contribution to the ICMLA2008 "Automated Micro-Array Classification Challenge". The design of our classifier is motivated by the special scenario encounte...
Donald Geman, Bahman Afsari, Aik Choon Tan, Daniel...
BMCBI
2007
133views more  BMCBI 2007»
15 years 6 months ago
Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data
Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. ...
Ivan G. Costa, Roland Krause, Lennart Opitz, Alexa...
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ICMLA
2010
15 years 3 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context
Background: Different microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little ov...
Gad Abraham, Adam Kowalczyk, Sherene Loi, Izhak Ha...