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EOR
2010
88views more  EOR 2010»
15 years 6 months ago
Mathematical programming approaches for generating p-efficient points
Abstract: Probabilistically constrained problems, in which the random variables are finitely distributed, are nonconvex in general and hard to solve. The p-efficiency concept has b...
Miguel A. Lejeune, Nilay Noyan
BMCBI
2006
158views more  BMCBI 2006»
15 years 6 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2006
121views more  BMCBI 2006»
15 years 6 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2007
105views more  BMCBI 2007»
15 years 6 months ago
Finding regulatory elements and regulatory motifs: a general probabilistic framework
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Erik van Nimwegen