6087 search results - page 739 / 1218 » Knowledge discovery methods |
189
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BMCBI
2010
15 years 7 months ago
2010
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
201
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BMCBI
2010
15 years 7 months ago
2010
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
188
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BMCBI
2010
15 years 7 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
211
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BMCBI
2008
15 years 7 months ago
2008
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
186
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BMCBI
2008
15 years 7 months ago
2008
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...