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BMCBI
2010
100views more  BMCBI 2010»
15 years 6 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2008
105views more  BMCBI 2008»
15 years 6 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
JCB
2007
136views more  JCB 2007»
15 years 6 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...
WWW
2007
ACM
16 years 7 months ago
Acquiring ontological knowledge from query logs
We present a method for acquiring ontological knowledge using search query logs. We first use query logs to identify important contexts associated with terms belonging to a semant...
Satoshi Sekine, Hisami Suzuki
DLOG
2007
15 years 9 months ago
Contextualization of a DL Knowledge Base
Abstract. In the paper we propose a method of structuring a knowledge base into hierarchically related contexts and present how this arrangement influences the structure of TBox a...
Krzysztof Goczyla, Wojciech Waloszek, Aleksander W...