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BMCBI
2010
107views more  BMCBI 2010»
15 years 7 months ago
Semantic annotation of morphological descriptions: an overall strategy
Background: Large volumes of morphological descriptions of whole organisms have been created as print or electronic text in a human-readable format. Converting the descriptions in...
Hong Cui
BMCBI
2010
136views more  BMCBI 2010»
15 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2007
128views more  BMCBI 2007»
15 years 7 months ago
Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
Oliviero Carugo
BMCBI
2006
181views more  BMCBI 2006»
15 years 7 months ago
Automatic pathway building in biological association networks
Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary f...
Anton Yuryev, Zufar Mulyukov, Ekaterina Kotelnikov...
BMCBI
2006
85views more  BMCBI 2006»
15 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen