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BMCBI
2007
118views more  BMCBI 2007»
15 years 6 months ago
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
Pierre de la Grange, Martin Dutertre, Margot Corre...
BMCBI
2007
89views more  BMCBI 2007»
15 years 6 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2007
167views more  BMCBI 2007»
15 years 6 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
CORR
2008
Springer
138views Education» more  CORR 2008»
15 years 6 months ago
Computing Minimum Spanning Trees with Uncertainty
Abstract. We consider the minimum spanning tree problem in a setting where information about the edge weights of the given graph is uncertain. Initially, for each edge e of the gra...
Thomas Erlebach, Michael Hoffmann 0002, Danny Kriz...
CORR
2010
Springer
117views Education» more  CORR 2010»
15 years 6 months ago
Reductions Between Expansion Problems
The Small-Set Expansion Hypothesis (Raghavendra, Steurer, STOC 2010) is a natural hardness assumption concerning the problem of approximating the edge expansion of small sets in g...
Prasad Raghavendra, David Steurer, Madhur Tulsiani