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JCNS
2010
103views more  JCNS 2010»
15 years 1 months ago
Efficient computation of the maximum a posteriori path and parameter estimation in integrate-and-fire and more general state-spa
A number of important data analysis problems in neuroscience can be solved using state-space models. In this article, we describe fast methods for computing the exact maximum a pos...
Shinsuke Koyama, Liam Paninski
CIDR
2003
125views Algorithms» more  CIDR 2003»
15 years 8 months ago
Crossing the Structure Chasm
It has frequently been observed that most of the world’s data lies outside database systems. The reason is that database systems focus on structured data, leaving the unstructur...
Alon Y. Halevy, Oren Etzioni, AnHai Doan, Zachary ...
BMCBI
2004
208views more  BMCBI 2004»
15 years 6 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
RECOMB
2007
Springer
16 years 6 months ago
Free Energy Estimates of All-Atom Protein Structures Using Generalized Belief Propagation
We present a technique for approximating the free energy of protein structures using Generalized Belief Propagation (GBP). The accuracy and utility of these estimates are then demo...
Hetunandan Kamisetty, Eric P. Xing, Christopher Ja...
CVBIA
2005
Springer
16 years 3 days ago
Analyzing Anatomical Structures: Leveraging Multiple Sources of Knowledge
Analysis of medical images, especially the extraction of anatomical structures, is a critical component of many medical applications: surgical planning and navigation, and populati...
W. Eric L. Grimson, Polina Golland