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BMCBI
2006
157views more  BMCBI 2006»
15 years 6 months ago
Comparison of protein interaction networks reveals species conservation and divergence
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Zhi Liang, Meng Xu, Maikun Teng, Liwen Niu
BMCBI
2004
135views more  BMCBI 2004»
15 years 6 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2007
181views more  BMCBI 2007»
15 years 6 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan
BMCBI
2010
142views more  BMCBI 2010»
15 years 6 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan