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BMCBI
2011
15 years 1 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
NAR
2010
194views more  NAR 2010»
15 years 1 months ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
ISMB
2007
15 years 8 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
SC
2005
ACM
16 years 1 days ago
SPICE: Simulated Pore Interactive Computing Environment
— SPICE aims to understand the vital process of translocation of biomolecules across protein pores by computing the free energy profile of the translocating biomolecule along th...
Shantenu Jha, Peter V. Coveney, Matt J. Harvey
LREC
2008
134views Education» more  LREC 2008»
15 years 8 months ago
Dependency-Based Relation Mining for Biomedical Literature
We describe techniques for the automatic detection of relationships among domain entities (e.g. genes, proteins, diseases) mentioned in the biomedical literature. Our approach is ...
Fabio Rinaldi, Gerold Schneider, Kaarel Kaljurand,...