1938 search results - page 162 / 388 » Interactive Protein Manipulation |
150
click to vote
BMCBI
2007
15 years 6 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
175
click to vote
BMCBI
2007
15 years 6 months ago
2007
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
164
click to vote
BMCBI
2005
15 years 6 months ago
2005
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
183
click to vote
BMCBI
2004
15 years 6 months ago
2004
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
207
click to vote
BMCBI
2011
14 years 10 months ago
2011
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...