1938 search results - page 129 / 388 » Interactive Protein Manipulation |
204
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BMCBI
2010
15 years 6 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
181
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BMCBI
2005
15 years 6 months ago
2005
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
187
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BMCBI
2010
15 years 6 months ago
2010
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
167
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NAR
2011
14 years 9 months ago
2011
Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a criti...
140
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BIOSYSTEMS
2007
15 years 6 months ago
2007
The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of mole...