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CPHYSICS
2006
127views more  CPHYSICS 2006»
15 years 6 months ago
GenAnneal: Genetically modified Simulated Annealing
A modification of the standard Simulated Annealing (SA) algorithm is presented for finding the global minimum of a continuous multidimensional, multimodal function. We report resu...
Ioannis G. Tsoulos, Isaac E. Lagaris
BMCBI
2007
94views more  BMCBI 2007»
15 years 6 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
145views more  BMCBI 2007»
15 years 6 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
JOT
2008
119views more  JOT 2008»
15 years 6 months ago
Revisiting Class Cohesion: An empirical investigation on several systems
Class cohesion is considered as one of most important object-oriented software attributes. Cohesion refers to the degree of relatedness between members in a class. High cohesion i...
Linda Badri, Mourad Badri, Alioune Badara Gueye
BMCBI
2005
117views more  BMCBI 2005»
15 years 6 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai