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BMCBI
2008
100views more  BMCBI 2008»
15 years 6 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2006
155views more  BMCBI 2006»
15 years 6 months ago
CAVER: a new tool to explore routes from protein clefts, pockets and cavities
Background: The main aim of this study was to develop and implement an algorithm for the rapid, accurate and automated identification of paths leading from buried protein clefts, ...
Martin Petrek, Michal Otyepka, Pavel Banás,...
BMCBI
2011
15 years 28 days ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
EVOW
2006
Springer
15 years 10 months ago
Robust SVM-Based Biomarker Selection with Noisy Mass Spectrometric Proteomic Data
Abstract. Computational analysis of mass spectrometric (MS) proteomic data from sera is of potential relevance for diagnosis, prognosis, choice of therapy, and study of disease act...
Elena Marchiori, Connie R. Jimenez, Mikkel West-Ni...
TWC
2010
15 years 1 months ago
Splitting algorithms for fast relay selection: generalizations, analysis, and a unified view
Relay selection for cooperative communications promises significant performance improvements, and is, therefore, attracting, considerable attention. While several criteria have be...
Virag Shah, Neelesh B. Mehta, Raymond Yim