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190
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BMCBI
2010
15 years 6 months ago
2010
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
147
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BMCBI
2010
15 years 6 months ago
2010
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
168
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BMCBI
2010
15 years 6 months ago
2010
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
183
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BMCBI
2010
15 years 6 months ago
2010
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
182
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BMCBI
2010
15 years 6 months ago
2010
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...