Background: Haplotypes extracted from human DNA can be used for gene mapping and other analysis of genetic patterns within and across populations. A fundamental problem is, howeve...
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
Background: Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific con...
Milana Frenkel-Morgenstern, Rachel Magid, Eran Eya...
In the STS-based mapping, we are requested to obtain the correct order of probes in a DNA sequence from a given set of fragments or equivalently a hybridization matrix A. It is wel...
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...