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BMCBI
2010
115views more  BMCBI 2010»
15 years 6 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
ISDA
2008
IEEE
16 years 18 days ago
Combining Clustering and Bayesian Network for Gene Network Inference
Gene network reconstruction is a multidisciplinary research area involving data mining, machine learning, statistics, ontologies and others. Reconstructed gene network allows us t...
Suhaila Zainudin, Safaai Deris
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
BMCBI
2007
111views more  BMCBI 2007»
15 years 6 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda