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BMCBI
2005
106views more  BMCBI 2005»
15 years 6 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
JGO
2008
101views more  JGO 2008»
15 years 6 months ago
Dynamic equilibria of group vaccination strategies in a heterogeneous population
Abstract In this paper we present an evolutionary variational inequality model of vaccination strategies games in a population with a known vaccine coverage profile over a certain ...
Monica-Gabriela Cojocaru
ML
2010
ACM
119views Machine Learning» more  ML 2010»
15 years 5 months ago
A cooperative coevolutionary algorithm for instance selection for instance-based learning
This paper presents a cooperative evolutionary approach for the problem of instance selection for instance based learning. The presented model takes advantage of one of the most r...
Nicolás García-Pedrajas, Juan Antoni...
BMCBI
2010
108views more  BMCBI 2010»
15 years 4 months ago
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Background: The opportunities for bacterial population genomics that are being realised by the application of parallel nucleotide sequencing require novel bioinformatics platforms...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2011
15 years 1 months ago
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments
Background: As the canonical code is not universal, different theories about its origin and organization have appeared. The optimization or level of adaptation of the canonical ge...
Jose Santos, Ángel Monteagudo