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» Improving the Modeling of Use Case Relationship
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BMCBI
2002
133views more  BMCBI 2002»
15 years 6 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
IFM
1999
Springer
15 years 10 months ago
Retrenchment and Punctured Simulation
: Some of the shortcomings of using refinement alone as the means of passing from high level simple models to actual detailed implementations are reviewed. Retrenchment is presente...
Richard Banach, Michael Poppleton
BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2007
153views more  BMCBI 2007»
15 years 6 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
GIS
2008
ACM
16 years 7 months ago
Quantifying spatial prepositions: an experimental study
Many aspects of spatial language concerned with relationships between spatial entities are essentially vague. Current GIS technology provides very little support for dealing with ...
Mark M. Hall, Christopher B. Jones