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146
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BMCBI
2010
15 years 6 months ago
2010
Background: Transcriptional regulatory network inference (TRNI) from large compendia of DNA microarrays has become a fundamental approach for discovering transcription factor (TF)...
171
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BMCBI
2010
15 years 6 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
163
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BMCBI
2008
15 years 6 months ago
2008
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
161
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BMCBI
2010
15 years 6 months ago
2010
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
178
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BMCBI
2007
15 years 6 months ago
2007
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...