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BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2005
78views more  BMCBI 2005»
15 years 6 months ago
Correlation test to assess low-level processing of high-density oligonucleotide microarray data
Background: There are currently a number of competing techniques for low-level processing of oligonucleotide array data. The choice of technique has a profound effect on subsequen...
Alexander Ploner, Lance D. Miller, Per Hall, Jonas...
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2005
189views more  BMCBI 2005»
15 years 6 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
TMI
2008
162views more  TMI 2008»
15 years 6 months ago
Generalized Tensor-Based Morphometry of HIV/AIDS Using Multivariate Statistics on Deformation Tensors
Abstract--This paper investigates the performance of a new multivariate method for tensor-based morphometry (TBM). Statistics on Riemannian manifolds are developed that exploit the...
Natasha Lepore, Caroline A. Brun, Yi-Yu Chou, Ming...
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