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BMCBI
2010
193views more  BMCBI 2010»
15 years 6 months ago
MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
Background: Mass spectrometry (MS) coupled with online separation methods is commonly applied for differential and quantitative profiling of biological samples in metabolomic as w...
Tomás Pluskal, Sandra Castillo, Alejandro V...
BMCBI
2010
88views more  BMCBI 2010»
15 years 6 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BMCBI
2007
97views more  BMCBI 2007»
15 years 6 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
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