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167
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BMCBI
2008
15 years 7 months ago
2008
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
171
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BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
15 years 7 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
154
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BMCBI
2007
15 years 7 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
164
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BMCBI
2007
15 years 7 months ago
2007
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
158
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BMCBI
2007
15 years 7 months ago
2007
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...