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BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2008
129views more  BMCBI 2008»
15 years 6 months ago
Prediction of the outcome of preoperative chemotherapy in breast cancer using DNA probes that provide information on both comple
Background: DNA microarray technology has emerged as a major tool for exploring cancer biology and solving clinical issues. Predicting a patient's response to chemotherapy is...
René Natowicz, Roberto Incitti, Euler Guima...
BMCBI
2008
116views more  BMCBI 2008»
15 years 6 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
COMPUTER
2008
84views more  COMPUTER 2008»
15 years 6 months ago
e-Science, caGrid, and Translational Biomedical Research
We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
Joel H. Saltz, Tahsin M. Kurç, Shannon Hast...
CORR
2008
Springer
176views Education» more  CORR 2008»
15 years 6 months ago
Analysis of Social Voting Patterns on Digg
The social Web is transforming the way information is created and distributed. Authoring tools, e.g., blog publishing services, enable users to quickly and easily publish content,...
Kristina Lerman, Aram Galstyan
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