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BMCBI
2010
152views more  BMCBI 2010»
15 years 6 months ago
Apples and oranges: avoiding different priors in Bayesian DNA sequence analysis
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
BMCBI
2010
138views more  BMCBI 2010»
15 years 6 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
CCR
2008
76views more  CCR 2008»
15 years 6 months ago
WebClass: adding rigor to manual labeling of traffic anomalies
Despite the flurry of anomaly-detection papers in recent years, effective ways to validate and compare proposed solutions have remained elusive. We argue that evaluating anomaly d...
Haakon Ringberg, Augustin Soule, Jennifer Rexford
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BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2005
86views more  BMCBI 2005»
15 years 6 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...