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BMCBI
2007
124views more  BMCBI 2007»
15 years 6 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
BMCBI
2008
118views more  BMCBI 2008»
15 years 6 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
DAC
2009
ACM
16 years 7 months ago
Generating test programs to cover pipeline interactions
Functional validation of a processor design through execution of a suite of test programs is common industrial practice. In this paper, we develop a high-level architectural speci...
Thanh Nga Dang, Abhik Roychoudhury, Tulika Mitra, ...
DAC
2001
ACM
16 years 7 months ago
Speculation Techniques for High Level Synthesis of Control Intensive Designs
The quality of synthesis results for most high level synthesis approaches is strongly a ected by the choice of control ow through conditions and loops in the input description. In...
Sumit Gupta, Nick Savoiu, Sunwoo Kim, Nikil D. Dut...
ICFP
2008
ACM
16 years 6 months ago
NixOS: a purely functional Linux distribution
Existing package and system configuration management tools suffer from an imperative model, where system administration actions such as upgrading packages or changes to system con...
Andres Löh, Eelco Dolstra