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BMCBI
2006
91views more  BMCBI 2006»
15 years 6 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2007
142views more  BMCBI 2007»
15 years 6 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...
BMCBI
2007
141views more  BMCBI 2007»
15 years 6 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
BMCBI
2007
115views more  BMCBI 2007»
15 years 6 months ago
A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
Background: Hidden Markov Models (HMMs) provide an excellent means for structure identification and feature extraction on stochastic sequential data. An HMM-with-Duration (HMMwD) ...
Stephen Winters-Hilt, Carl Baribault