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BMCBI
2005
116views more  BMCBI 2005»
15 years 6 months ago
WEBnm@: a web application for normal mode analyses of proteins
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
Siv Midtun Hollup, Gisle Sælensminde, Nathal...
BMCBI
2005
190views more  BMCBI 2005»
15 years 6 months ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
BMCBI
2005
121views more  BMCBI 2005»
15 years 6 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
BMCBI
2005
124views more  BMCBI 2005»
15 years 6 months ago
Internet-based profiler system as integrative framework to support translational research
Background: Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to dev...
Robert Kim, Francesca Demichelis, Jeffery Tang, Al...
BMCBI
2005
97views more  BMCBI 2005»
15 years 6 months ago
Clustering the annotation space of proteins
Background: Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. Results: Her...
Victor Kunin, Christos A. Ouzounis
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