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167
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BMCBI
2007
15 years 6 months ago
2007
Background: Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. I...
177
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BMCBI
2007
15 years 6 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
178
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BMCBI
2007
15 years 6 months ago
2007
Background: Automated methods for assembling families of orthologous genes include those based on sequence similarity scores and those based on phylogenetic approaches. The first ...
210
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BMCBI
2007
15 years 6 months ago
2007
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...