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BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BMCBI
2010
176views more  BMCBI 2010»
15 years 6 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
Inkyung Jung, Akihisa Matsuyama, Minoru Yoshida, D...
BMCBI
2010
175views more  BMCBI 2010»
15 years 6 months ago
Towards high performance computing for molecular structure prediction using IBM Cell Broadband Engine - an implementation perspe
Background: RNA structure prediction problem is a computationally complex task, especially with pseudo-knots. The problem is well-studied in existing literature and predominantly ...
S. P. T. Krishnan, Sim Sze Liang, Bharadwaj Veerav...
BMCBI
2008
87views more  BMCBI 2008»
15 years 6 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
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