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163
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BMCBI
2010
15 years 6 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
170
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BMCBI
2010
15 years 6 months ago
2010
Background: In the current era of scientific research, efficient communication of information is paramount. As such, the nature of scholarly and scientific communication is changi...
142
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BMCBI
2010
15 years 6 months ago
2010
Background: The construction of interaction networks between proteins is central to understanding the underlying biological processes. However, since many useful relations are exc...
185
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BMCBI
2010
15 years 6 months ago
2010
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
146
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BMCBI
2010
15 years 6 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...