8582 search results - page 1528 / 1717 » Here or There |
196
click to vote
BMCBI
2010
15 years 6 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
161
click to vote
BMCBI
2010
15 years 6 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
168
click to vote
BMCBI
2010
15 years 6 months ago
2010
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
170
click to vote
BMCBI
2010
15 years 6 months ago
2010
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
175
click to vote
BMCBI
2010
2010
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
15 years 6 months ago
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...